Experiment about single - strand dna breaks in permanent middle cerebral artery occlusion of rats 單鏈斷裂損傷的實(shí)驗(yàn)研究
The orf1 proteins of all four chinese senv isolates had two motifs ( ftl and yxxk ) which were conserved in replication - associated proteins . in all four chinese senv isolates , the putative non - structure orf2 protein had a cav - like region . the putative orf3 protein had a serine - rich tract preceded by a cluster of basic amino acids ( r and k ) . database scaning suggested this region had high a percentage of homology with dna topoisomerase i protein of d . melanogaster , and might play an important role in the replication of such single - stranded dna viruses 所有這四個(gè)中國(guó)分離株,均保留了o即1中與復(fù)制有關(guān)的保守序列( ftl和yxxk ) :在推測(cè)是非結(jié)構(gòu)蛋白的orfz中均含有cav樣保守區(qū)w ‘ x7一h一x3一c一xl一c一xs一h ; orf3蛋白的堿性氨基酸(精氨酸和賴氨酸)簇后緊接著一個(gè)富含絲氨酸的區(qū)域,與d . molanogaster的dna拓?fù)洚悩?gòu)酶i有一定的同源性,推測(cè)在單鏈dna的復(fù)制中起作用。